Advanced Programming
In this section, you will find information on:
Extended bolus
What is it?
An amount of bolus insulin equally spread and delivered over a specific amount of time.
What can it do?
When eating foods that are high in fat or protein, or if you take pramlintide with a meal, you may benefit from insulin delivered over a longer amount of time. This will prevent initial hypoglycemia and subsequent hyperglycemia.

The insulin pump or continuous subcutaneous insulin infusion device (CSII) continuously administers rapid acting insulin into the fatty tissue beneath the skin. The insulin pump is especially suited to covering different patterns of insulin resistance or sensitivity throughout the day. The pump also has multiple bolus profiles including standard, dual , multiple and extended boluses.
Dual bolus
What is it?
A combination of immediate bolus insulin delivery, plus an extended bolus.
What can it do?
A dual bolus provides insulin coverage for foods that contain both high fat or high protein with simple carbohydrates.
Insulin-on-board (IOB)
What is it?
IOB is a program that keeps track of how long a bolus of insulin is working. You set your IOB for a certain amount of time. Depending upon the dose of rapid-acting insulin (analog insulin), it is usually set for 4 hours. Individuals with expecially high bolus doses , i.e. over 15-20 units per bolus, may need an IOB of 5-6 hours.
What are the benefits of this pre-programming?
- Helps prevent “stacking” insulin, or excessive correction of a high glucose, that can result in hypoglycemia
- Helps avoid giving too little insulin in treating high glucose for fear of hypoglycemia
Example
- 2 p.m. glucose: 250 mg/dl (entered by user)
- IOB shows: 2.3 units still effective (from previous bolus delivered at lunch)
- ISF: 1 unit per 50
- Target glucose: 110 mg/dl
- Calculation: 250 minus 110 = 140
- 140 divided by 50 = 2.8
- 2.8 minus 2.3 = .5
- Recommendation: 0.5 unit for a high glucose of 250 at 2 p.m.